HBV Target gene Detail Information

> PIGU Gene Search Result

Gene Information

Gene Name	PIGU
Gene ID	128869
Gene Full Name	phosphatidylinositol glycan anchor biosynthesis class U
Gene Alias	GAB1; CDC91L1
Transcripts	ENSG00000101464
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Gene Function	Oncogene
Uniport_ID	Q9H490
HGNC ID	HGNC:15791
VEGA ID	OTTHUMG00000032304
OMIM ID	608528
String ID	9606.ENSP00000217446
PharmGKB ID	PA162399506

Target gene [PIGU] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011781	chr20	8			8	View
1012822	chr20	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PIGU expression and immune infiltrating cell level correlation result in HBV+ samples
PIGU expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).