HBV Target gene Detail Information

> PIGR Gene Search Result

Gene Information

Gene Name	PIGR
Gene ID	5284
Gene Full Name	polymeric immunoglobulin receptor
Transcripts	ENSG00000162896
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted membrane proteins
Uniport_ID	P01833
HGNC ID	HGNC:8968
VEGA ID	OTTHUMG00000036581
OMIM ID	173880
String ID	9606.ENSP00000348888
PharmGKB ID	PA33300

Target gene [PIGR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002599	chr1	105	75	66	246	View
1005127	chr1	48	6	7	61	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PIGR expression and immune infiltrating cell level correlation result in HBV+ samples
PIGR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).