HIV Target gene Detail Information

> PIAS1 Gene Search Result

Gene Information

Gene Name	PIAS1
Gene ID	8554
Gene Full Name	protein inhibitor of activated STAT 1
Gene Alias	GBP; ZMIZ3; DDXBP1; GU/RH-II
Transcripts	ENSG00000033800
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	O75925
HGNC ID	HGNC:2752
VEGA ID	OTTHUMG00000172645
OMIM ID	603566
String ID	9606.ENSP00000249636
PharmGKB ID	PA33285

Target gene [PIAS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000855	chr15	217	40	7	264	View
4003041	chr15	70	1		71	View
4008793	chr15	13	1		14	View
4009015	chr15	11	1	1	13	View
4009445	chr15	6	2	3	11	View
4011884	chr15	6			6	View
4012230	chr15	5			5	View
4012800	chr15	2	1	1	4	View
4013434	chr15	3			3	View
4013789	chr15	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PIAS1 expression and immune infiltrating cell level correlation result in HIV+ samples
PIAS1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PIAS1 expression and immune infiltrating cell level correlation result in HIV+ samples
PIAS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).