HBV Target gene Detail Information

> PI4KB Gene Search Result


Gene Information
Gene Name PI4KB
Gene ID 5298
Gene Full Name phosphatidylinositol 4-kinase beta
Gene Alias NPIK; PI4K92; PIK4CB; PI4KBETA; PI4K-BETA; PI4KIIIBETA
Transcripts ENSG00000143393
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9UBF8
HGNC ID HGNC:8984
VEGA ID OTTHUMG00000012348
OMIM ID 602758
String ID 9606.ENSP00000357869
Drugbank ID BE0009467; BE0009513
Drug (Cytoscape Annotation) LapatinibDitosylate;Pazopanib Hydrochloride
PharmGKB ID PA162399420
Target gene [PI4KB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002772 chr1 34 126 47 207 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PI4KB expression and immune infiltrating cell level correlation result in HBV+ samples
PI4KB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).