HBV Target gene Detail Information

> PI4KA Gene Search Result

Gene Information

Gene Name	PI4KA
Gene ID	5297
Gene Full Name	phosphatidylinositol 4-kinase alpha
Gene Alias	PIK4CA; PMGYCHA; pi4K230; PI4K-ALPHA
Transcripts	ENSG00000241973
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P42356
HGNC ID	HGNC:8983
VEGA ID	OTTHUMG00000167440
OMIM ID	600286
String ID	9606.ENSP00000255882
PharmGKB ID	PA162399305

Target gene [PI4KA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012040	chr22	4	3		7	View
1404726	chr22	14	4		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PI4KA expression and immune infiltrating cell level correlation result in HBV+ samples
PI4KA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).