HBV Target gene Detail Information

> PI4KA Gene Search Result


Gene Information
Gene Name PI4KA
Gene ID 5297
Gene Full Name phosphatidylinositol 4-kinase alpha
Gene Alias PIK4CA; PMGYCHA; pi4K230; PI4K-ALPHA
Transcripts ENSG00000241973
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P42356
HGNC ID HGNC:8983
VEGA ID OTTHUMG00000167440
OMIM ID 600286
String ID 9606.ENSP00000255882
PharmGKB ID PA162399305
Target gene [PI4KA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012040 chr22 4 3 7 View
1404726 chr22 14 4 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PI4KA expression and immune infiltrating cell level correlation result in HBV+ samples
PI4KA expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).