HIV Target gene Detail Information

> PHYKPL Gene Search Result

Gene Information

Gene Name	PHYKPL
Gene ID	85007
Gene Full Name	5-phosphohydroxy-L-lysine phospho-lyase
Gene Alias	PHLU; AGXT2L2
Transcripts	ENSG00000175309
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q8IUZ5
HGNC ID	HGNC:28249
VEGA ID	OTTHUMG00000130892
OMIM ID	614683
String ID	9606.ENSP00000310978
Drugbank ID	BE0002164
PharmGKB ID	PA162376015

Target gene [PHYKPL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000922	chr5	110	72	68	250	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PHYKPL expression and immune infiltrating cell level correlation result in HIV+ samples
PHYKPL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).