HTLV1 Target gene Detail Information

> PHKG1 Gene Search Result

Gene Information

Gene Name	PHKG1
Gene ID	5260
Gene Full Name	phosphorylase kinase catalytic subunit gamma 1
Gene Alias	PHKG
Transcripts	ENSG00000164776
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q16816
HGNC ID	HGNC:8930
VEGA ID	OTTHUMG00000023869
OMIM ID	172470
String ID	9606.ENSP00000445440
Drugbank ID	BE0009466
PharmGKB ID	PA33271

Target gene [PHKG1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004553	chr7	55	42	15	112	View
6013763	chr7	14	4		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PHKG1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PHKG1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PHKG1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PHKG1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PHKG1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PHKG1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).