HBV Target gene Detail Information

> PHKB Gene Search Result

Gene Information

Gene Name	PHKB
Gene ID	5257
Gene Full Name	phosphorylase kinase regulatory subunit beta
Transcripts	ENSG00000102893
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q93100
HGNC ID	HGNC:8927
VEGA ID	OTTHUMG00000133102
OMIM ID	172490
String ID	9606.ENSP00000313504
PharmGKB ID	PA33268

Target gene [PHKB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002077	chr16	251	56	45	352	View
1003394	chr16	119	13	5	137	View
1014138	chr16	4			4	View
1018374	chr16				0	View
1403394	chr16	119	13	5	137	View
1404693	chr16	51	5	7	63	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PHKB expression and immune infiltrating cell level correlation result in HBV+ samples
PHKB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).