HIV Target gene Detail Information

> PHF8 Gene Search Result

Gene Information

Gene Name	PHF8
Gene ID	23133
Gene Full Name	PHD finger protein 8
Gene Alias	KDM7B; JHDM1F; MRXSSD; ZNF422
Transcripts	ENSG00000172943
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9UPP1
HGNC ID	HGNC:20672
VEGA ID	OTTHUMG00000021622
OMIM ID	300560
String ID	9606.ENSP00000350676
PharmGKB ID	PA134889361

Target gene [PHF8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016692	chrX				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PHF8 expression and immune infiltrating cell level correlation result in HIV+ samples
PHF8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).