HIV Target gene Detail Information

> PHF6 Gene Search Result

Gene Information

Gene Name	PHF6
Gene ID	84295
Gene Full Name	PHD finger protein 6
Gene Alias	BFLS; BORJ; CENP-31
Transcripts	ENSG00000156531
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q8IWS0
HGNC ID	HGNC:18145
VEGA ID	OTTHUMG00000022453
OMIM ID	300414
String ID	9606.ENSP00000329097
PharmGKB ID	PA33263

Target gene [PHF6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009288	chrX	10	2		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PHF6 expression and immune infiltrating cell level correlation result in HIV+ samples
PHF6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).