HBV Target gene Detail Information

> PHEX Gene Search Result

Gene Information

Gene Name	PHEX
Gene ID	5251
Gene Full Name	phosphate regulating endopeptidase homolog X-linked
Gene Alias	HYP; PEX; XLH; HPDR; HYP1; LXHR; HPDR1
Transcripts	ENSG00000102174
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins
Uniport_ID	P78562
HGNC ID	HGNC:8918
VEGA ID	OTTHUMG00000021241
OMIM ID	300550
String ID	9606.ENSP00000368682
PharmGKB ID	PA33258

Target gene [PHEX] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1014244	chrX	1		3	4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PHEX expression and immune infiltrating cell level correlation result in HBV+ samples
PHEX expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).