HIV Target gene Detail Information

> PHACTR2 Gene Search Result

Gene Information

Gene Name	PHACTR2
Gene ID	9749
Gene Full Name	phosphatase and actin regulator 2
Gene Alias	C6orf56
Transcripts	ENSG00000112419
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O75167
HGNC ID	HGNC:20956
VEGA ID	OTTHUMG00000015732
OMIM ID	608724
String ID	9606.ENSP00000417038
PharmGKB ID	PA134944445

Target gene [PHACTR2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002055	chr6	44	59	12	115	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PHACTR2 expression and immune infiltrating cell level correlation result in HIV+ samples
PHACTR2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PHACTR2 expression and immune infiltrating cell level correlation result in HIV+ samples
PHACTR2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).