HIV Target gene Detail Information

> PGS1 Gene Search Result

Gene Information

Gene Name	PGS1
Gene ID	9489
Gene Full Name	phosphatidylglycerophosphate synthase 1
Transcripts	ENSG00000087157
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q32NB8
HGNC ID	HGNC:30029
VEGA ID	OTTHUMG00000177514
OMIM ID	614942
String ID	9606.ENSP00000262764
PharmGKB ID	PA142671180

Target gene [PGS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000947	chr17	194	38	9	241	View
4002214	chr19	102	3		105	View
4003003	chr17	41	18	13	72	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PGS1 expression and immune infiltrating cell level correlation result in HIV+ samples
PGS1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PGS1 expression and immune infiltrating cell level correlation result in HIV+ samples
PGS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).