HTLV1 Target gene Detail Information

> PGM5 Gene Search Result

Gene Information

Gene Name	PGM5
Gene ID	5239
Gene Full Name	phosphoglucomutase 5
Gene Alias	PGMRP
Transcripts	ENSG00000154330
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q15124
HGNC ID	HGNC:8908
VEGA ID	OTTHUMG00000019966
OMIM ID	600981
String ID	9606.ENSP00000379678
PharmGKB ID	PA33245

Target gene [PGM5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005690	chr9	64	5	13	82	View
6017049	chr9	4	1	6	11	View
6018497	chr9	9			9	View
6027015	chr9	1	1		2	View
6032296	chr9				0	View
6032996	chr9				0	View
6100323	chr9	95	199	96	390	View
6100324	chr9	51	15	36	102	View
6100325	chr9	53	9	1	63	View
6100326	chr9	117	123	119	359	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PGM5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PGM5 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PGM5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PGM5 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PGM5 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PGM5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).