HTLV1 Target gene Detail Information

> PGAP2 Gene Search Result

Gene Information

Gene Name	PGAP2
Gene ID	27315
Gene Full Name	post-GPI attachment to proteins 2
Gene Alias	FRAG1; MRT17; MRT21; HPMRS3; CWH43-N
Transcripts	ENSG00000148985
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Microtubules;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9UHJ9
HGNC ID	HGNC:17893
VEGA ID	OTTHUMG00000012238
OMIM ID	615187
String ID	9606.ENSP00000278243
PharmGKB ID	PA165543520

Target gene [PGAP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000418	chr11	1452	126	103	1681	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PGAP2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PGAP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).