HIV Target gene Detail Information

> PGAP1 Gene Search Result

Gene Information

Gene Name	PGAP1
Gene ID	80055
Gene Full Name	post-GPI attachment to proteins 1
Gene Alias	Bst1; MRT42; SPG67; ISPD3024
Transcripts	ENSG00000197121
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q75T13
HGNC ID	HGNC:25712
VEGA ID	OTTHUMG00000132743
OMIM ID	611655
String ID	9606.ENSP00000346809
PharmGKB ID	PA162399235

Target gene [PGAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002954	chr2	2	72		74	View
4005708	chr2	29		1	30	View
4007587	chr2	13	5		18	View
4007978	chr2	4	13		17	View
4009950	chr2	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PGAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PGAP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PGAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PGAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).