HBV Target gene Detail Information

> PFKFB3 Gene Search Result

Gene Information

Gene Name	PFKFB3
Gene ID	5209
Gene Full Name	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Gene Alias	PFK2; IPFK2; iPFK-2
Transcripts	ENSG00000170525
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q16875
HGNC ID	HGNC:8874
VEGA ID	OTTHUMG00000017621
OMIM ID	605319
String ID	9606.ENSP00000443319
PharmGKB ID	PA33213

Target gene [PFKFB3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010071	chr10	10	3		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PFKFB3 expression and immune infiltrating cell level correlation result in HBV+ samples
PFKFB3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).