HTLV1 Target gene Detail Information

> PEX5L Gene Search Result

Gene Information

Gene Name	PEX5L
Gene ID	51555
Gene Full Name	peroxisomal biogenesis factor 5 like
Gene Alias	PXR2; PEX5R; PXR2B; PEX5RP; TRIP8b
Transcripts	ENSG00000114757
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8IYB4
HGNC ID	HGNC:30024
VEGA ID	OTTHUMG00000157363
OMIM ID	611058
String ID	9606.ENSP00000419975
PharmGKB ID	PA134892044

Target gene [PEX5L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005190	chr3	42	29	22	93	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PEX5L expression and immune infiltrating cell level correlation result in HTLV1+ samples
PEX5L expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PEX5L expression and immune infiltrating cell level correlation result in HTLV1+ samples
PEX5L expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PEX5L expression and immune infiltrating cell level correlation result in HTLV1+ samples
PEX5L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).