HBV Target gene Detail Information

> PEX1 Gene Search Result

Gene Information

Gene Name	PEX1
Gene ID	5189
Gene Full Name	peroxisomal biogenesis factor 1
Gene Alias	ZWS; ZWS1; HMLR1; PBD1A; PBD1B
Transcripts	ENSG00000127980
Virus	HBV
Gene Type	protein coding
HPA Location Info	Peroxisomes;
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O43933
HGNC ID	HGNC:8850
VEGA ID	OTTHUMG00000023926
OMIM ID	602136
String ID	9606.ENSP00000248633
PharmGKB ID	PA33192

Target gene [PEX1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001044	chr7	1058	47	3	1108	View
1001045	chr7	1058	47	3	1108	View
1001046	chr7	1058	47	3	1108	View
1400162	chr7	21	4	3	28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PEX1 expression and immune infiltrating cell level correlation result in HBV+ samples
PEX1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).