HIV Target gene Detail Information

> PELP1 Gene Search Result

Gene Information

Gene Name	PELP1
Gene ID	27043
Gene Full Name	proline, glutamate and leucine rich protein 1
Gene Alias	MNAR; P160
Transcripts	ENSG00000141456
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q8IZL8
HGNC ID	HGNC:30134
VEGA ID	OTTHUMG00000177831
OMIM ID	609455
String ID	9606.ENSP00000301396
PharmGKB ID	PA142671186

Target gene [PELP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001417	chr17	4	163	1	168	View
4005107	chr17	1	35		36	View
4009297	chr17	11	1		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PELP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PELP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PELP1 expression and immune infiltrating cell level correlation result in HIV+ samples
PELP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).