HIV Target gene Detail Information

> PELI1 Gene Search Result

Gene Information

Gene Name	PELI1
Gene ID	57162
Gene Full Name	pellino E3 ubiquitin protein ligase 1
Transcripts	ENSG00000197329
Virus	HIV
Gene Type	protein coding
HPA Location Info	Intermediate filaments;Nucleoli;Nucleoplasm;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q96FA3
HGNC ID	HGNC:8827
VEGA ID	OTTHUMG00000129511
OMIM ID	614797
String ID	9606.ENSP00000351789
PharmGKB ID	PA33172

Target gene [PELI1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001039	chr2	167	56	4	227	View
4001251	chr2	119	64	6	189	View
4002495	chr2	51	36	5	92	View
4007054	chr2	13	6	2	21	View
4008819	chr2	7	7		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PELI1 expression and immune infiltrating cell level correlation result in HIV+ samples
PELI1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PELI1 expression and immune infiltrating cell level correlation result in HIV+ samples
PELI1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).