HIV Target gene Detail Information

> PDXDC1 Gene Search Result

Gene Information

Gene Name	PDXDC1
Gene ID	23042
Gene Alias	LP8165
Transcripts	ENSG00000179889
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6P996
HGNC ID	HGNC:28995
VEGA ID	OTTHUMG00000191265
OMIM ID	614244
String ID	9606.ENSP00000379691
PharmGKB ID	PA162399182

Target gene [PDXDC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001027	chr16	190	34	4	228	View
4001463	chr16	149	12		161	View
4001682	chr16	63	30	47	140	View
4003750	chr16	50	5		55	View
4004990	chr16	15	13	9	37	View
4005975	chr16	25	3		28	View
4010833	chr16	6		2	8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDXDC1 expression and immune infiltrating cell level correlation result in HIV+ samples
PDXDC1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PDXDC1 expression and immune infiltrating cell level correlation result in HIV+ samples
PDXDC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).