HBV Target gene Detail Information

> PDSS2 Gene Search Result


Gene Information
Gene Name PDSS2
Gene ID 57107
Gene Full Name decaprenyl diphosphate synthase subunit 2
Gene Alias DLP1; hDLP1; COQ10D3; C6orf210; bA59I9.3
Transcripts ENSG00000164494
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q86YH6
HGNC ID HGNC:23041
VEGA ID OTTHUMG00000059359
OMIM ID 610564
String ID 9606.ENSP00000358033
PharmGKB ID PA134957167
Target gene [PDSS2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010249 chr6 12 1 13 View
1014050 chr6 1 3 4 View
1014562 chr6 2 1 3 View
1014563 chr6 2 1 3 View
1017292 chr6 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PDSS2 expression and immune infiltrating cell level correlation result in HBV+ samples
PDSS2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).