HIV Target gene Detail Information

> PDPR Gene Search Result

Gene Information

Gene Name	PDPR
Gene ID	55066
Gene Full Name	pyruvate dehydrogenase phosphatase regulatory subunit
Gene Alias	PDP3
Transcripts	ENSG00000090857
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NCN5
HGNC ID	HGNC:30264
VEGA ID	OTTHUMG00000176963
OMIM ID	617835
String ID	9606.ENSP00000288050
PharmGKB ID	PA166048996

Target gene [PDPR] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004840	chr16	28	11		39	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDPR expression and immune infiltrating cell level correlation result in HIV+ samples
PDPR expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PDPR expression and immune infiltrating cell level correlation result in HIV+ samples
PDPR expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).