HBV Target gene Detail Information

> PDP2 Gene Search Result


Gene Information
Gene Name PDP2
Gene ID 57546
Gene Full Name pyruvate dehyrogenase phosphatase catalytic subunit 2
Gene Alias PPM2B; PDPC 2; PPM2C2
Transcripts ENSG00000172840
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9P2J9
HGNC ID HGNC:30263
VEGA ID OTTHUMG00000137512
OMIM ID 615499
String ID 9606.ENSP00000309548
PharmGKB ID PA165450460
Target gene [PDP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002330 chr16 45 142 106 293 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PDP2 expression and immune infiltrating cell level correlation result in HBV+ samples
PDP2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).