HIV Target gene Detail Information

> PDLIM5 Gene Search Result

Gene Information

Gene Name	PDLIM5
Gene ID	10611
Gene Full Name	PDZ and LIM domain 5
Gene Alias	L9; ENH; LIM; ENH1
Transcripts	ENSG00000163110
Virus	HIV
Gene Type	protein coding
HPA Location Info	Focal adhesion sites;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q96HC4
HGNC ID	HGNC:17468
VEGA ID	OTTHUMG00000130973
OMIM ID	605904
String ID	9606.ENSP00000480359
PharmGKB ID	PA134917248

Target gene [PDLIM5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000253	chr4	143	153	346	642	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDLIM5 expression and immune infiltrating cell level correlation result in HIV+ samples
PDLIM5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PDLIM5 expression and immune infiltrating cell level correlation result in HIV+ samples
PDLIM5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).