Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> PDLIM1 Gene Search Result


Gene Information
Gene Name PDLIM1
Gene ID 9124
Gene Full Name PDZ and LIM domain 1
Gene Alias CLIM1; CLP36; CLP-36; hCLIM1; HEL-S-112
Transcripts ENSG00000107438
Virus HBV
Gene Type protein coding
HPA Location Info Actin filaments;Cell Junctions;Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID O00151
HGNC ID HGNC:2067
VEGA ID OTTHUMG00000018810
OMIM ID 605900
String ID 9606.ENSP00000360305
PharmGKB ID PA33158
Target gene [PDLIM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007931 chr10 17 6 23 View
1010065 chr10 13 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PDLIM1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PDLIM1 expression: Low -> High
Lollipop of PDLIM1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PDLIM1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PDLIM1 expression and immune infiltrating cell level correlation result in HBV+ samples
PDLIM1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).