HIV Target gene Detail Information

> PDIK1L Gene Search Result

Gene Information

Gene Name	PDIK1L
Gene ID	149420
Gene Full Name	PDLIM1 interacting kinase 1 like
Gene Alias	CLIK1L; STK35L2
Transcripts	ENSG00000175087
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8N165
HGNC ID	HGNC:18981
VEGA ID	OTTHUMG00000007511
OMIM ID	610785
String ID	9606.ENSP00000363389
PharmGKB ID	PA134959839

Target gene [PDIK1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000426	chr1	170	140	161	471	View
4000608	chr1	327	14	3	344	View
4002728	chr1	81	1		82	View
4004791	chr1	34	5		39	View
4005654	chr1	28	2		30	View
4006352	chr1	9	9	7	25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDIK1L expression and immune infiltrating cell level correlation result in HIV+ samples
PDIK1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PDIK1L expression and immune infiltrating cell level correlation result in HIV+ samples
PDIK1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).