HTLV1 Target gene Detail Information

> PDGFRB Gene Search Result


Gene Information
Gene Name PDGFRB
Gene ID 5159
Gene Full Name platelet derived growth factor receptor beta
Gene Alias IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1
Transcripts ENSG00000113721
Virus HTLV1
Gene Type protein coding
HPA Location Info Vesicles;Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P09619
HGNC ID HGNC:8804
VEGA ID OTTHUMG00000130053
OMIM ID 173410
String ID 9606.ENSP00000261799
Drugbank ID BE0000205
Drug (Cytoscape Annotation) Sorafenib Tosylate;Sunitinib Malate;Pazopanib Hydrochloride;Bosutinib;Nilotinib;Dasatinib;ImatinibMesylate;Vandetanib;Axitinib
PharmGKB ID PA33148
FDA Approved Drug Sorafenib;Sunitinib;Regorafenib;Axitinib;Pazopanib;Imatinib
Target gene [PDGFRB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6013207 chr5 14 6 20 View
6016547 chr5 10 1 1 12 View
6018559 chr5 7 1 1 9 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).