HPV Target gene Detail Information

> PDGFRA Gene Search Result

Gene Information

Gene Name	PDGFRA
Gene ID	5156
Gene Full Name	platelet derived growth factor receptor alpha
Gene Alias	CD140A; PDGFR2; PDGFR-2
Transcripts	ENSG00000134853
Virus	HPV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Nucleoplasm;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins
Gene Function	Oncogene
Uniport_ID	P16234
HGNC ID	HGNC:8803
VEGA ID	OTTHUMG00000128699
OMIM ID	173490
String ID	9606.ENSP00000257290
Drugbank ID	BE0000852
Drug (Cytoscape Annotation)	Sorafenib Tosylate;ImatinibMesylate;Nilotinib;Vandetanib;Sunitinib Malate;Pazopanib Hydrochloride;Dasatinib;Axitinib
PharmGKB ID	PA33147
FDA Approved Drug	Sunitinib;Olaratumab;Avapritinib;Imatinib

Target gene [PDGFRA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402799	chr4	103	18	13	134	View
5403749	chr4	8			8	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).