HBV Target gene Detail Information

> PDGFD Gene Search Result


Gene Information
Gene Name PDGFD
Gene ID 80310
Gene Full Name platelet derived growth factor D
Gene Alias IEGF; SCDGFB; MSTP036; SCDGF-B
Transcripts ENSG00000170962
Virus HBV
Gene Type protein coding
HPA Location Info Golgi apparatus;Vesicles;Predicted to be secreted;
HPA Protein Class Info Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins
Uniport_ID Q9GZP0
HGNC ID HGNC:30620
VEGA ID OTTHUMG00000165953
OMIM ID 609673
String ID 9606.ENSP00000376865
Drugbank ID BE0003411
PharmGKB ID PA134892327
Target gene [PDGFD] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006007 chr11 12 33 45 View
1400086 chr11 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PDGFD expression and immune infiltrating cell level correlation result in HBV+ samples
PDGFD expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).