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EBV Target gene Detail Information

> PDE9A Gene Search Result


Gene Information
Gene Name PDE9A
Gene ID 5152
Gene Full Name phosphodiesterase 9A
Gene Alias HSPDE9A2
Transcripts ENSG00000160191
Virus EBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID O76083
HGNC ID HGNC:8795
VEGA ID OTTHUMG00000086825
OMIM ID 602973
String ID 9606.ENSP00000291539
Drugbank ID BE0003134; BE0004922
PharmGKB ID PA33143
Target gene [PDE9A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000345 chr21 19 11 30 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of PDE9A expression and immune infiltrating cell level correlation result in EBV+ samples
PDE9A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).