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EBV Target gene Detail Information

> PDE7B Gene Search Result


Gene Information
Gene Name PDE7B
Gene ID 27115
Gene Full Name phosphodiesterase 7B
Gene Alias bA472E5.1
Transcripts ENSG00000171408
Virus EBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID Q9NP56
HGNC ID HGNC:8792
VEGA ID OTTHUMG00000015641
OMIM ID 604645
String ID 9606.ENSP00000310661
Drugbank ID BE0000627; BE0004922
PharmGKB ID PA33140
Target gene [PDE7B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
3000089 chr6 125 63 15 203 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE102203 (GEO) B-cell lymphoma 9 Plasmablastic lymphomas (EBV+)(6), Plasmablastic lymphomas (EBV-)(3)
GSE100458 (GEO) Burkitt lymphoma 14 Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO) Burkitt lymphoma 12 Burkitt lymphoma cell line Awia (EBV+)(12)
GSE135644 (GEO) Gastric carcinoma 10 Gastric adenocarcinoma cell line AGS (5), Gastric adenocarcinoma cell line AGS (EBV+)(5)
GSE45919 (GEO) Infectious mononucleosis 24 Infectious mononucleosis (IM)(EBV+)(3), Normal (9), Latent EBV (12)
GSE85599 (GEO) Infectious mononucleosis 17 Chronic active EBV infection (EBV+)(5), Acute infectious mononucleosis (EBV+)(6), Normal (6)
GSE58240 (GEO) Multiple sclerosis 32 Multiple sclerosis IFN-β treated (EBV+)(16), Multiple sclerosis untreated (EBV+)(16)
GSE12452 (GEO) Nasopharyngeal carcinoma 41 Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE102203

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE100458

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE42867

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE135644

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE45919

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE85599

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE58240

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High

> Dataset: GSE12452

HeatMap of cell type fractions in all samples Lollipop of PDE7B expression and immune infiltrating cell level correlation result in EBV+ samples
PDE7B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).