HIV Target gene Detail Information

> PDE2A Gene Search Result

Gene Information

Gene Name	PDE2A
Gene ID	5138
Gene Full Name	phosphodiesterase 2A
Gene Alias	PDE2A1; PED2A4; cGSPDE; CGS-PDE
Transcripts	ENSG00000186642
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	O00408
HGNC ID	HGNC:8777
VEGA ID	OTTHUMG00000102045
OMIM ID	602658
String ID	9606.ENSP00000334910
Drugbank ID	BE0002085; BE0003393; BE0004922
PharmGKB ID	PA33125

Target gene [PDE2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011177	chr11	7			7	View
4011178	chr11	7			7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDE2A expression and immune infiltrating cell level correlation result in HIV+ samples
PDE2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).