HBV Target gene Detail Information

> PDE1C Gene Search Result

Gene Information

Gene Name	PDE1C
Gene ID	5137
Gene Full Name	phosphodiesterase 1C
Gene Alias	Hcam3; DFNA74; hCam-3; cam-PDE 1C
Transcripts	ENSG00000154678
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	Q14123
HGNC ID	HGNC:8776
VEGA ID	OTTHUMG00000023836
OMIM ID	602987
String ID	9606.ENSP00000379496
Drugbank ID	BE0004849; BE0004922
PharmGKB ID	PA33124

Target gene [PDE1C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009489	chr7	13		2	15	View
1009736	chr7	6	3	5	14	View
1012540	chr7	2	4		6	View
1014838	chr7		3		3	View
1014839	chr7		3		3	View
1018880	chr7				0	View
1402564	chr7	13		2	15	View
1402565	chr7	2	4		6	View
1402566	chr7	6	3	5	14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PDE1C expression and immune infiltrating cell level correlation result in HBV+ samples
PDE1C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).