HBV Target gene Detail Information

> PDE1A Gene Search Result

Gene Information

Gene Name	PDE1A
Gene ID	5136
Gene Full Name	phosphodiesterase 1A
Gene Alias	HCAM1; HCAM-1; HSPDE1A; CAM-PDE 1A; CAM-PDE-1A
Transcripts	ENSG00000115252
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	P54750
HGNC ID	HGNC:8774
VEGA ID	OTTHUMG00000132596
OMIM ID	171890
String ID	9606.ENSP00000410309
Drugbank ID	BE0003565; BE0004922
PharmGKB ID	PA33122

Target gene [PDE1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010969	chr2	7	3		10	View
1014776	chr2	1		2	3	View
1019680	chr2				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PDE1A expression and immune infiltrating cell level correlation result in HBV+ samples
PDE1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).