HBV Target gene Detail Information

> PDE11A Gene Search Result

Gene Information

Gene Name	PDE11A
Gene ID	50940
Gene Full Name	phosphodiesterase 11A
Gene Alias	PPNAD2
Transcripts	ENSG00000128655
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID	Q9HCR9
HGNC ID	HGNC:8773
VEGA ID	OTTHUMG00000154188
OMIM ID	604961
String ID	9606.ENSP00000286063
Drugbank ID	BE0003558; BE0004922
PharmGKB ID	PA33121

Target gene [PDE11A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001933	chr2	253	90	68	411	View
1004352	chr2	5	77	2	84	View
1400153	chr2	1	3	2	6	View
1402824	chr2	253	90	68	411	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PDE11A expression and immune infiltrating cell level correlation result in HBV+ samples
PDE11A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).