HIV Target gene Detail Information

> PDCD6IP Gene Search Result

Gene Information

Gene Name	PDCD6IP
Gene ID	10015
Gene Full Name	programmed cell death 6 interacting protein
Gene Alias	AIP1; ALIX; HP95; DRIP4
Transcripts	ENSG00000170248
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8WUM4
HGNC ID	HGNC:8766
VEGA ID	OTTHUMG00000130751
OMIM ID	608074
String ID	9606.ENSP00000411825
PharmGKB ID	PA33116

Target gene [PDCD6IP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008113	chr3	9	4	3	16	View
4012409	chr3	4	1		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PDCD6IP expression and immune infiltrating cell level correlation result in HIV+ samples
PDCD6IP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PDCD6IP expression and immune infiltrating cell level correlation result in HIV+ samples
PDCD6IP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).