HIV Target gene Detail Information

> PCMTD1 Gene Search Result


Gene Information
Gene Name PCMTD1
Gene ID 115294
Gene Full Name protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
Transcripts ENSG00000168300
Virus HIV
Gene Type protein coding
HPA Location Info Plasma membrane;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q96MG8
HGNC ID HGNC:30483
VEGA ID OTTHUMG00000164246
String ID 9606.ENSP00000353739
PharmGKB ID PA142671194
Target gene [PCMTD1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4013537 chr8 3 3 View
4015897 chr8 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PCMTD1 expression and immune infiltrating cell level correlation result in HIV+ samples
PCMTD1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of PCMTD1 expression and immune infiltrating cell level correlation result in HIV+ samples
PCMTD1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).