HBV Target gene Detail Information

> PCK1 Gene Search Result


Gene Information
Gene Name PCK1
Gene ID 5105
Gene Full Name phosphoenolpyruvate carboxykinase 1
Gene Alias PCKDC; PEPCK1; PEPCKC; PEPCK-C
Transcripts ENSG00000124253
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Citric acid cycle related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID P35558
HGNC ID HGNC:8724
VEGA ID OTTHUMG00000032825
OMIM ID 614168
String ID 9606.ENSP00000319814
Drugbank ID BE0000906
PharmGKB ID PA33069
Target gene [PCK1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010131 chr20 8 5 13 View
1010132 chr20 8 5 13 View
1010138 chr20 8 5 13 View
1010139 chr20 8 5 13 View
1011961 chr20 8 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PCK1 expression and immune infiltrating cell level correlation result in HBV+ samples
PCK1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).