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HBV Target gene Detail Information

> PCGF6 Gene Search Result


Gene Information
Gene Name PCGF6
Gene ID 84108
Gene Full Name polycomb group ring finger 6
Gene Alias MBLR; RNF134
Transcripts ENSG00000156374
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9BYE7
HGNC ID HGNC:21156
VEGA ID OTTHUMG00000018982
OMIM ID 607816
String ID 9606.ENSP00000358862
PharmGKB ID PA134887110
Target gene [PCGF6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001689 chr10 504 19 523 View
1001721 chr10 497 19 516 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of PCGF6 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
PCGF6 expression: Low -> High
Lollipop of PCGF6 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of PCGF6 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of PCGF6 expression and immune infiltrating cell level correlation result in HBV+ samples
PCGF6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).