HTLV1 Target gene Detail Information

> PCGF2 Gene Search Result

Gene Information

Gene Name	PCGF2
Gene ID	7703
Gene Full Name	polycomb group ring finger 2
Gene Alias	MEL-18; RNF110; ZNF144
Transcripts	ENSG00000278644
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P35227
HGNC ID	HGNC:12929
VEGA ID	OTTHUMG00000191275
OMIM ID	600346
String ID	9606.ENSP00000482063
PharmGKB ID	PA37516

Target gene [PCGF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001381	chr17	199	26	232	457	View
6003613	chr17	127	12	11	150	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PCGF2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PCGF2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PCGF2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PCGF2 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PCGF2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PCGF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).