HIV Target gene Detail Information

> PCF11 Gene Search Result

Gene Information

Gene Name	PCF11
Gene ID	51585
Gene Full Name	PCF11, cleavage and polyadenylation factor subunit
Transcripts	ENSG00000165494
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Mitochondria;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O94913
HGNC ID	HGNC:30097
VEGA ID	OTTHUMG00000167031
OMIM ID	608876
String ID	9606.ENSP00000298281
PharmGKB ID	PA142671196

Target gene [PCF11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004478	chr11	36	7		43	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PCF11 expression and immune infiltrating cell level correlation result in HIV+ samples
PCF11 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PCF11 expression and immune infiltrating cell level correlation result in HIV+ samples
PCF11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).