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HPV Target gene Detail Information

> PCDHB15 Gene Search Result


Gene Information
Gene Name PCDHB15
Gene ID 56121
Gene Full Name protocadherin beta 15
Gene Alias PCDH-BETA15
Transcripts ENSG00000113248
Virus HPV
Gene Type protein coding
HPA Location Info Mitochondria;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9Y5E8
HGNC ID HGNC:8686
VEGA ID OTTHUMG00000129609
OMIM ID 606341
String ID 9606.ENSP00000231173
PharmGKB ID PA33031
Target gene [PCDHB15] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403107 chr5 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of PCDHB15 expression and immune infiltrating cell level correlation result in HPV+ samples
PCDHB15 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of PCDHB15 expression and immune infiltrating cell level correlation result in HPV+ samples
PCDHB15 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of PCDHB15 expression and immune infiltrating cell level correlation result in HPV+ samples
PCDHB15 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of PCDHB15 expression and immune infiltrating cell level correlation result in HPV+ samples
PCDHB15 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of PCDHB15 expression and immune infiltrating cell level correlation result in HPV+ samples
PCDHB15 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of PCDHB15 expression and immune infiltrating cell level correlation result in HPV+ samples
PCDHB15 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).