HBV Target gene Detail Information

> PCDH15 Gene Search Result

Gene Information

Gene Name	PCDH15
Gene ID	65217
Gene Full Name	protocadherin related 15
Gene Alias	USH1F; CDHR15; DFNB23
Transcripts	ENSG00000150275
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q96QU1
HGNC ID	HGNC:14674
VEGA ID	OTTHUMG00000018259
OMIM ID	605514
String ID	9606.ENSP00000363068
PharmGKB ID	PA32999

Target gene [PCDH15] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010266	chr10	1	12		13	View
1011478	chr10	1	3	5	9	View
1016460	chr10		1		1	View
1017461	chr10	1			1	View
1019811	chr10				0	View
1100086	chr10	21	3	1	25	View
1100087	chr10	21	3	1	25	View
1404689	chr10				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PCDH15 expression and immune infiltrating cell level correlation result in HBV+ samples
PCDH15 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).