HBV Target gene Detail Information

> PCCA Gene Search Result

Gene Information

Gene Name	PCCA
Gene ID	5095
Gene Full Name	propionyl-CoA carboxylase subunit alpha
Transcripts	ENSG00000175198
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P05165
HGNC ID	HGNC:8653
VEGA ID	OTTHUMG00000017284
OMIM ID	232000
String ID	9606.ENSP00000365462
Drugbank ID	BE0000492
PharmGKB ID	PA32992

Target gene [PCCA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001736	chr13	78	284	147	509	View
1019676	chr13				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PCCA expression and immune infiltrating cell level correlation result in HBV+ samples
PCCA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).