HIV Target gene Detail Information

> PCBP2 Gene Search Result

Gene Information

Gene Name	PCBP2
Gene ID	5094
Gene Full Name	poly(rC) binding protein 2
Gene Alias	HNRPE2; HNRNPE2; hnRNP-E2
Transcripts	ENSG00000197111
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q15366
HGNC ID	HGNC:8648
VEGA ID	OTTHUMG00000169439
OMIM ID	601210
String ID	9606.ENSP00000352438
PharmGKB ID	PA32987

Target gene [PCBP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009370	chr12	11	1		12	View
4009371	chr12	11	1		12	View
4010396	chr12	8	1		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of PCBP2 expression and immune infiltrating cell level correlation result in HIV+ samples
PCBP2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of PCBP2 expression and immune infiltrating cell level correlation result in HIV+ samples
PCBP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).