HTLV1 Target gene Detail Information

> PCBP1 Gene Search Result

Gene Information

Gene Name	PCBP1
Gene ID	5093
Gene Full Name	poly(rC) binding protein 1
Gene Alias	HNRPX; HNRPE1; hnRNP-X; HEL-S-85; hnRNP-E1
Transcripts	ENSG00000169564
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytoplasmic bodies;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q15365
HGNC ID	HGNC:8647
VEGA ID	OTTHUMG00000129645
OMIM ID	601209
String ID	9606.ENSP00000305556
PharmGKB ID	PA32986

Target gene [PCBP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6100214	chr2	1850	670	224	2744	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of PCBP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PCBP1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of PCBP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PCBP1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of PCBP1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
PCBP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).