HIV Target gene Detail Information

> PATL2 Gene Search Result


Gene Information
Gene Name PATL2
Gene ID 197135
Gene Full Name PAT1 homolog 2
Gene Alias OOMD4; Pat1a; hPat1a
Transcripts ENSG00000282077
Virus HIV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID C9JE40
HGNC ID HGNC:33630
VEGA ID OTTHUMG00000191131
OMIM ID 614661
String ID 9606.ENSP00000416673
PharmGKB ID PA164724408
Target gene [PATL2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001559 chr15 5 74 72 151 View
4002320 chr15 22 42 36 100 View
4002642 chr15 4 35 47 86 View
4003372 chr15 9 18 36 63 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of PATL2 expression and immune infiltrating cell level correlation result in HIV+ samples
PATL2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of PATL2 expression and immune infiltrating cell level correlation result in HIV+ samples
PATL2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).