HBV Target gene Detail Information

> PARP8 Gene Search Result

Gene Information

Gene Name	PARP8
Gene ID	79668
Gene Full Name	poly(ADP-ribose) polymerase family member 8
Gene Alias	ARTD16; pART16
Transcripts	ENSG00000151883
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Midbody ring;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8N3A8
HGNC ID	HGNC:26124
VEGA ID	OTTHUMG00000096969
String ID	9606.ENSP00000281631
PharmGKB ID	PA134903201

Target gene [PARP8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004792	chr5	16	18	35	69	View
1013101	chr5	2	3		5	View
1402825	chr5	2	3		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of PARP8 expression and immune infiltrating cell level correlation result in HBV+ samples
PARP8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).